Investigation of the formation of tin(II)-flouride complex by potentiometric titration

Abstract

The purpose of present investigation was to determine optimal condition for obtaining a stable Sn(II) complex with sodium flouride.

Measurements were performed by a potentiometric titration method, using a selective electrode with a flouride membrane, at pH 5, constant ionic strength and 22 ± 1°C. Stability constants were determined for both water and water-ethanol mixtures.

The obtained types of tin(II) complexes with flouride anion varied in dependence of Sn(II)/F molar ratio, which also influences the biological behavior of the tin colloid obtained by ^99mTc labelling of tin flouride complexes observed on experimental animals.