Current view on radiation-induced heart disease and methods of its diagnosis

R. Muratov, S. Babenko, M. N. Sorkomov
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引用次数: 0

Abstract

In recent years, cardiologists and cardiovascular surgeons are increasingly encountering radiation-induced heart disease (RIHD) in their practice. This complication is described in literature but is poorly understood and clinically challenging. Radiation therapy (RT) is widely used in the treatment of many cancers. Despite the considerable risk of RT complications, it is used in 20–55% of cancer patients. Radiation-associated cardiotoxicity appears to be delayed, typically 10 to 30 years following treatment. Mediastinal irradiation significantly increases the risk of non-ischemic cardiomyopathy. Recent reviews estimate the prevalence of radiation-induced cardiomyopathy at more than 10%. Therefore, it is important to understand the pathophysiology of RIHD, consider risk factors associated with radiation injury, and detect the condition early.
辐射性心脏病的研究现状及诊断方法
近年来,心脏病专家和心血管外科医生在他们的实践中越来越多地遇到辐射引起的心脏病(RIHD)。这种并发症在文献中有描述,但了解甚少,临床上具有挑战性。放射治疗(RT)广泛应用于多种癌症的治疗。尽管有相当大的RT并发症风险,但它在20-55%的癌症患者中使用。辐射相关的心脏毒性似乎是延迟的,通常在治疗后10至30年。纵隔照射显著增加非缺血性心肌病的风险。最近的评论估计,辐射引起的心肌病的患病率超过10%。因此,了解RIHD的病理生理学,考虑与辐射损伤相关的危险因素,并及早发现病情是很重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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