{"title":"Combination of 5‐ALA photodynamic therapy, surgery and superficial X‐ray for the treatment of keloid","authors":"Wenbo Bu, Fang Fang, Mengli Zhang, Jun Chen","doi":"10.1111/phpp.12506","DOIUrl":null,"url":null,"abstract":"Keloids are refractory to treatment. Surgery, radiation therapy, laser therapy and intralesional injection of various agents have all been used either alone or in various combinations but with largely transient success. Although postoperative radiation therapy is relatively effective, it still has a recurrence rate of approximately 20%1 . In addition, postoperative radiotherapy has also increased the risk of tumours2 . To date, there is emerging evidence for the role of photodynamic therapy (PDT) in treating hypertrophic and keloid scars3-4 . In this study, we prospectively compared the efficacy and safety of surgery and superficial X-ray radiation therapy with or without the PDT treatment for keloids. This article is protected by copyright. All rights reserved.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"45 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/phpp.12506","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Keloids are refractory to treatment. Surgery, radiation therapy, laser therapy and intralesional injection of various agents have all been used either alone or in various combinations but with largely transient success. Although postoperative radiation therapy is relatively effective, it still has a recurrence rate of approximately 20%1 . In addition, postoperative radiotherapy has also increased the risk of tumours2 . To date, there is emerging evidence for the role of photodynamic therapy (PDT) in treating hypertrophic and keloid scars3-4 . In this study, we prospectively compared the efficacy and safety of surgery and superficial X-ray radiation therapy with or without the PDT treatment for keloids. This article is protected by copyright. All rights reserved.