Efficacy of Dialectical Comprehensive Treatment of Traditional Chinese Medicine in Patients with Chronic Stable Heart Failure: A Randomized Controlled Trial

IF 1.8 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiology Research and Practice Pub Date : 2022-05-12 DOI:10.1155/2022/5408063

Lixiang Yang, Yuanyuan Chen, Fei Lou, Xiaoxia Zhao, Jia Zhou

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引用次数: 0

Abstract

The treatment of chronic stable heart failure (CSHF) with integrated traditional Chinese and Western medicine has been of wide concern. We mainly discuss the clinical efficacy of TCM decoction combined with acupuncture and moxibustion (A&M) in CSHF treatment on the basis of syndrome differentiation and treatment (SDT). The control group was given conventional cardiac rehabilitation (CCR), and the treatment group was given TCM decoction combined with A&M treatment based on SDT on the basis of conventional cardiac rehabilitation. The clinical efficacy and cardiopulmonary exercise testing (CPET) indicators were evaluated. Left ventricular ejection fraction (LVEF), NT-proBNP, myocardial ischemia threshold (MIT), and 6-minute walking distance (6MWD) were measured by ultrasound, ELISA, electrocardiogram, and 6MWD test. After treatment, the clinical efficacy, LVEF, and 6MWD of the treatment group were better than in the control group. The NT-proBNP plasma level and MIT in the treatment group were lower than in the control group. The treatment group had enhanced AT, VO2 Peak, VO2 Peak/HR, and Peak power and decreased resting systolic pressure and peak systolic pressure, and the difference was statistically significant. Dialectical comprehensive treatment of TCM could effectively improve cardiac function and clinical treatment effect, which was worthy of clinical application.

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中医辨证综合疗法治疗慢性稳定型心力衰竭的疗效:随机对照试验

中西医结合治疗慢性稳定型心力衰竭(CSHF)已受到广泛关注。我们在辨证论治(SDT)的基础上，主要探讨中药汤剂结合针灸(A&M)治疗CSHF的临床疗效。对照组给予常规心脏康复治疗(CCR)，治疗组在常规心脏康复治疗的基础上给予中药汤剂联合A&M治疗，以SDT为基础。评价两组临床疗效及心肺运动试验(CPET)指标。采用超声、ELISA、心电图、6MWD检测左室射血分数(LVEF)、NT-proBNP、心肌缺血阈值(MIT)、6分钟步行距离(6MWD)。治疗后，治疗组临床疗效、LVEF、6MWD均优于对照组。治疗组NT-proBNP血浆水平和MIT均低于对照组。治疗组AT、VO2 Peak、VO2 Peak/HR、Peak power均升高，静息收缩压和峰值收缩压均降低，差异有统计学意义。中医辨证综合治疗能有效改善心功能，提高临床治疗效果，值得临床推广应用。

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来源期刊

Cardiology Research and Practice Medicine-Cardiology and Cardiovascular Medicine

CiteScore

4.40

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Cardiology Research and Practice is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies that focus on the diagnosis and treatment of cardiovascular disease. The journal welcomes submissions related to systemic hypertension, arrhythmia, congestive heart failure, valvular heart disease, vascular disease, congenital heart disease, and cardiomyopathy.