Synthesis, Characterization, and Biological Evaluation Of [1,2,4 ]-Triazole-3yl]Sulfanyl Acetamide Derivative

Abstract

A significant portion of recent papers is in the field of Mercapto substituted Triazole moiety  received considerable attention in the literature.Characterization and Antibacterial activity against important medically Gram positive Bacteria likely Actinomyces, Clostridium, Mycobacterium, Strptococci, Staphylococci and Nocardia.Triazole is a class of N-Bridged  Heterocyclic compounds especially in Chemotherapy. Triazole moiety seems to be very small but 1,2,4-Triazole derivatives have wide range of potential antibacterial activities against drug-resistant pathogens.Hybridization shows a high potential to develop novel drugs,reduce toxicity,and improve Pharmacokinetic profiles.More effective antibacterial studies might be obtained by the hybridization of  1,2,4-Triazole  mercapto moiety. A number of clinically effective antibacterial drugs become more effective. Therefore, we shed, herein, more light on novel synthetic drug and its antibacterial activity.