Haemophagocytic lymphohistiocytosis during pregnancy: a case presentation and literature review.

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Case Reports in Perinatal Medicine Pub Date : 2022-03-04 eCollection Date: 2022-01-01 DOI:10.1515/crpm-2021-0004

Larissa Fávero Vanraes, Veerle Beckers, Kim Van Berkel, Leonardo Gucciardo, Gilles Faron

引用次数: 0

Abstract

Objectives: Haemophagocytic lymphohistiocytosis (HLH) is a potentially fatal disorder of the immune system that typically occurs in the paediatric population. Diagnosing this rare disease in the adult population is challenging, particularly during pregnancy.

Case presentation: We present a case of a gravid patient developing HLH at week 13 of gestation undergoing a medical termination of pregnancy at 27 weeks due to anhydramnios and associated stopped foetal growth.

Conclusions: Disease triggers could vary from a simple viral infection to the pregnancy as such causing the disorder. Treatment should benefit the mother and limit the foetal harm.

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妊娠期嗜血球性淋巴组织细胞增多症一例报告及文献复习

摘要:目的噬血细胞性淋巴组织细胞增多症(HLH)是一种潜在的致命性免疫系统疾病，通常发生在儿科人群中。在成年人群中诊断这种罕见疾病具有挑战性，特别是在怀孕期间。病例介绍我们提出一例妊娠患者在妊娠13周发展HLH经历医学终止妊娠27周由于羊水和相关胎儿停止生长。结论:疾病的触发因素可能从简单的病毒感染到导致疾病的妊娠。治疗应该有利于母亲，限制对胎儿的伤害。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Perinatal Medicine OBSTETRICS & GYNECOLOGY-

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期刊介绍： Case Reports in Perinatal Medicine is a double-blind peer-reviewed journal. The objective of the new journal is very similar to that of JPM. In addition to evidence-based studies, practitioners in clinical practice esteem especially exemplary reports of cases that reveal specific manifestations of diseases, its progress or its treatment. We consider case reports and series to be brief reports describing an isolated clinical case or a small number of cases. They may describe new or uncommon diagnoses, unusual outcomes or prognosis, new or infrequently used therapies and side effects of therapy not usually discovered in clinical trials. They represent the basic concept of experiences for studies on representative groups for further evidence-based research. The potential roles of case reports and case series are: Recognition and description of new diseases Detection of drug side effects (adverse or beneficial) Study of mechanisms of disease Medical education and audit Recognition of rare manifestations of disease.