Association between Admission Hyperglycemia and Outcome in Actue Ischemic Stroke Cases: An Observational Study

Bangladesh Journal of Neuroscience Pub Date : 2016-01-31 DOI:10.3329/bjn.v32i1.57410

P. Das, M. Islam, S. Sarkar, Narayan Chandra Kundu, Touhidur Rahman

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Abstract

Background: A high proportion of patients suffering from an acute stressful condition asuch as stroke or myocardial infarction may develop hyperglycemia even in the absence of a preexisting diagnosis of diabetes. The study evaluates the effect of hyperglycemia in the severity and outcome during the acute phase of stroke. Methods: This was a descriptive cross-sectional study. Baseline variables (eg: age, sex, smoking, hypertension, diabetes OHA/insulin) and outcome measures (mortaily, disability) were statistically analysed and compared with a control group of 50 patients of acute ischemic storke without admission hyperglycemia. Result: the base line characteristis of the two patient groups were comparable. The 1st week mortality was 16% in case group and 2% in the control group. the 30 days mortality in the case group and control group was 28% and 12% respectively, 58.33% were disabled & dependent in the hyperglycemia group, in comparison to 36.36% subjects in the control group. Conclusion: Admission hyperglycemia seems worsen the outcome and functional disability during the acute phase of Ischemic stroke. Admission glucose level is an important risk factor and should be immediately treated to reduce morbitidity & mortality in acute Ischemic stroke cases Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 28-33

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急性缺血性脑卒中患者入院时高血糖与转归的关系:一项观察性研究

背景:高比例的急性应激性疾病(如中风或心肌梗死)患者即使在没有糖尿病诊断的情况下也可能出现高血糖。该研究评估了高血糖对脑卒中急性期严重程度和预后的影响。方法:采用描述性横断面研究。对基线变量(如年龄、性别、吸烟、高血压、糖尿病OHA/胰岛素)和结局指标(死亡率、致残率)进行统计分析，并与对照组50例入院时无高血糖的急性缺血性卒中患者进行比较。结果:两组患者的基线特征具有可比性。病例组第1周死亡率为16%，对照组为2%。病例组和对照组的30天死亡率分别为28%和12%，高血糖组的残疾和依赖率为58.33%，对照组为36.36%。结论:入院时高血糖可加重缺血性脑卒中急性期的预后和功能障碍。入院时血糖水平是一个重要的危险因素，应立即治疗，以降低急性缺血性卒中病例的发病率和死亡率。Vol. 32 (1): 28-33

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Bangladesh Journal of Neuroscience

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