CentroidNet：a light-weight，fast nuclei centroid detection model for breast Ki67 scoring

Abstract

： Objective Breast cancer - prognostic Ki67 score can be as a key indicator for the proliferation rate of malignant （ invasive ） cells. Negative and positive nuclei detection is an essential part of Ki67 scoring. An automated algorithm for nuclei detection can alleviate the negative impact of intra/inter - observer variation and labor - intensive nuclei counting. In