Endovascular Stenting of Vertebral Artery Dissection in Acute Ischemic Stroke

Mehrnoush Gorjian, S. Raymond, M. Koch, A. Patel
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Abstract

Background: Vertebral artery (VA) dissection causing acute stroke is commonly treated with anticoagulation and rarely requires stenting. While stenting for atherosclerotic stenosis of VA is an established and efficient treatment option, the safety of stenting for VA dissection has not been studied. Case information: We report the technical challenges associated with stenting of a proximal VA dissection in a 74 year-old male with NIHSSS > 20 outside of the time window for thrombolytic therapy presenting with acute basilar artery thrombus and a hypoplastic contralateral VA. Methods: A coronary Drug-Eluting Stent (DES) was implemented in right VA following balloon angioplasty and basilar artery thrombolysis to maintain the patency of the dissected area in proximal VA. Results: The procedure was completed without complication. Postoperative Digital Subtraction Angiography (DSA) confirmed the patency of the vertebrobasilar system. There was no evidence of significant residual stenosis in the right vertebral artery on the follow up Computed Tomography Angiography (CTA) 2 months after the stent placement. Conclusion: Endovascular stenting of proximal VA dissection in the setting of acute ischemic stroke is relatively safe and feasible. It could be particularly considered in patients ineligible for IV thrombolysis with a hypoplastic contralateral VA. Further studies are needed to evaluate the long-term safety and efficacy of stenting for VA dissection.
急性缺血性脑卒中椎动脉夹层血管内支架植入术
背景:引起急性脑卒中的椎动脉夹层通常用抗凝治疗,很少需要支架植入术。虽然血管内动脉粥样硬化性狭窄的支架置入术是一种成熟且有效的治疗选择,但血管夹层支架置入术的安全性尚未得到研究。病例信息:我们报告了一名74岁男性NIHSSS患者在时间窗外进行溶栓治疗的技术挑战,该患者表现为急性基底动脉血栓和对侧VA发育不全。方法:在球囊血管成形术和基底动脉溶栓后,在右侧VA植入冠状动脉药物洗脱支架(DES),以维持VA近端解剖区域的通畅。手术顺利完成,没有并发症。术后数字减影血管造影(DSA)证实椎基底动脉系统通畅。在支架放置2个月后的随访ct血管造影(CTA)中未发现明显的右侧椎动脉残余狭窄。结论:血管内支架置入术治疗急性缺血性脑卒中是相对安全可行的。对于不适合静脉溶栓且对侧室间隔发育不全的患者,尤其需要考虑静脉溶栓。需要进一步的研究来评估支架置入室间隔夹层的长期安全性和有效性。
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