Phytoconstituents profiling and antioxidant potential of Wrightia tinctoria R. Br.

Current Botany Pub Date : 2023-03-10 DOI:10.25081/cb.2023.v14.8228

S. Rajkumar, G. Sathyaprabha, M. Mathanmohun

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引用次数: 1

Abstract

In the Indian traditional system of medicine, Wrightia tinctoria R.Br. (Apocyanaceae) is recognized as a biologically effective therapeutic plant for the treatment of jaundice. It is a natural medicinal tree possessing antidiabetic, anti-inflammatory, hepatoprotective, antinociceptive, antifungal, antibacterial, antipsoriatic, antiviral, anthelmintic, anticancerous, analgesic, antipyretic, and aphrodisiac activities. Methanolic extract of W. tinctoria plant was investigated with Gas Chromatography–Mass Spectrometry (GC-MS), Fourier transform infrared spectroscopy (FTIR) and the antioxidant activity of W. tinctoria was analysed by most probable hydrogen peroxide scavenging (H2O2) activity, DPPH activity and Thiobarbutaric acid. The phytochemical in W. tinctoria leaf and bark have been assessed by GC-MS analysis. GC-MS analysis of W. tinctoria methanolic extract exposed the existence of the GC-MS chromatograms of 10 peaks in the leaf and 20 peaks in the bark. The FTIR spectroscopy analyses were identified by various functional compounds in the extracts with distinctive peak values. The FTIR analysis of methanolic leaf extracts of W. tinctoria confirmed the presence of alcohol, amine, alkane, carboxylic acid, sulfur compounds, halogen compounds and alkyne which showed major peaks. Also the methanolic bark extracts of W. tinctoria confirmed the presence of amines, phenol, alcohols, alkane, aldehydes, carboxylic acid, nitrogen compounds, sulfur compounds, and halogen compounds which also exhibited major peaks. Significant antioxidant activity is displayed by the plant part of leaf and bark sample. The results obtained in the determination of antioxidant activity of MEWT displayed considerable free radical scavenging capacity against DPPH which generated free radicals. This study includes the identification of phytochemicals and antioxidant potential of methanolic and aqueous extract of W. tinctoria which assist in therapeutic claims about this species in the traditional medicinal plant system.

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白桦植物成分分析及抗氧化潜力研究。

在印度的传统医学体系中，白花草R.Br。(Apocyanaceae)被认为是治疗黄疸的生物有效的治疗植物。它是一种具有抗糖尿病、抗炎、保肝、抗结核、抗真菌、抗菌、抗银屑病、抗病毒、驱虫药、抗癌、镇痛、解热、壮阳等作用的天然药用树木。采用气相色谱-质谱联用(GC-MS)、傅里叶变换红外光谱(FTIR)等方法对青花楸植物甲醇提取物进行了研究，并通过最可能过氧化氢清除(H2O2)活性、DPPH活性和硫代巴丁酸活性分析了青花楸的抗氧化活性。采用气相色谱-质谱联用分析方法对白栎叶和树皮中的植物化学成分进行了分析。GC-MS分析结果表明，白花楸甲醇提取物在叶中有10个峰，在树皮中有20个峰。FTIR光谱分析表明，提取物中的各种功能化合物具有不同的峰值。通过红外光谱分析，发现黄樟叶甲醇提取物中存在醇类、胺类、烷烃类、羧酸类、硫类、卤素类和炔类化合物，并以醇类化合物为主峰。此外，白栎树皮甲醇提取物的主要成分有胺类、酚类、醇类、烷烃类、醛类、羧酸类、氮化合物、硫化合物和卤素化合物。叶和树皮样品的植物部分显示出显著的抗氧化活性。MEWT抗氧化活性测定结果显示，MEWT对产生自由基的DPPH具有较强的自由基清除能力。本研究包括鉴定植物化学物质和抗氧化潜力的甲醇和水提取物，这有助于该物种在传统药用植物系统的治疗主张。

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Current Botany

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