Primary Central Nervous System Lymphoma with Lateral Ventricle Involvement

Y. Oie, K. Murayama, S. Nagahisa, M. Abe, H. Toyama, K. Katada
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Abstract

A 77-year-old woman presented with worsening cognitive impairment, nausea and vomiting. Computed tomography (CT) of the head revealed a high-density mass that symmetrically filled both lateral ventricles. Magnetic resonance imaging (MRI) showed an enhanced mass with T1 and T2 prolongation and restricted diffusion on diffusion weighted imaging (DWI). Diagnosis was delayed until a post-mortem examination, which revealed the mass as a primary central nervous system lymphoma (PCNSL). A high-intensity tumor on DWI with lateral ventricle involvement should raise the possibility of PCNSL.
原发性中枢神经系统淋巴瘤伴侧脑室受累
77岁女性,表现为认知障碍加重、恶心和呕吐。头部计算机断层扫描(CT)显示高密度肿块对称地填充两侧侧脑室。磁共振成像(MRI)示肿块增强,T1、T2延长,弥散加权成像(DWI)扩散受限。诊断被推迟到尸检,发现肿块为原发性中枢神经系统淋巴瘤(PCNSL)。DWI上高强度肿瘤累及侧脑室应提高PCNSL的可能性。
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