Design of Highly Selective Cu2+ Fluorescent Probe Based on Pyrene Derivatives

Abstract

A new probe P was synthesized and characterized from pyrene formaldehyde. The probe showed good selectivity for Cu2+ over other metal ions in ethanol-water solution (Vethanol:Vwater=3.5:1.5, pH 6.5, 0.02 M HEPES). With the increasing of Cu2+ concentration (2-10 μM), the P-Cu2+ system displayed excellent linear relationship at 464 nm with the detection limit down to 0.66 μM.