Efficacy of the bioactive compounds of medicinal importance in the leaves of Lantana camara L. and Andrographis paniculata (Burm. f.) Wall. ex Nees.

IOSR Journal of Pharmacy and Biological Sciences Pub Date : 2017-06-01 DOI:10.9790/3008-1203073336

Maria Cheenickal, Romilly Margaret Mendez

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Abstract

The present study includes the phytochemical detection and antimicrobial activity of the leaves of Lantana camara L. and Andrographis paniculata (Burm. f.) Wall. ex Nees. Phytochemical screening of the leaf extract of leaves shade dried indicated the presence of flavonoids, terpenoids, tannins, alkaloids, steroids and glycosides. The antibacterial activity of ethanolic and aqueous extracts of leaves of Lantana camara and Andrographis paniculata were evaluated against the human pathogenic bacteria like Staphylococcus aureus and Pseudomonas aeruginosa by well diffusion method. Among the extracts analysed ethanolic extracts showed promising results whereas aqueous extracts did not report any zone of inhibition. The ethanol leaf extract (200μg/ml) showed maximum inhibition against Pseudomonas aeruginosa (16mm) and Staphylococcus aureus (16mm). Phytochemical tests carried out showed that the antibacterial activity of plant Lantana camara and Andrographis paniculata leaves was due to the presence of phytochemical compounds present in it.

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山楂叶和穿心莲叶中药用活性物质的药效研究。f。)墙。交货需要雇。

本文主要研究了山楂叶和穿心莲叶的植物化学检测及抑菌活性。f。)墙。交货需要雇。遮荫干燥叶提取物的植物化学筛选表明，其中含有黄酮类、萜类、单宁类、生物碱类、类固醇类和苷类化合物。采用孔扩散法研究了山楂叶和穿心莲叶乙醇提取物和水提物对金黄色葡萄球菌和铜绿假单胞菌的抑菌活性。在分析的提取物中，乙醇提取物显示出有希望的结果，而水提取物没有报告任何抑制区。乙醇叶提取物(200μg/ml)对铜绿假单胞菌(16mm)和金黄色葡萄球菌(16mm)的抑制作用最大。植物化学实验表明，山楂叶和穿心莲叶具有抗菌活性是由于其含有植物化学成分。

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IOSR Journal of Pharmacy and Biological Sciences

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