Antidiabetic potential of medicinal plants from the Peruvian Amazon: A review

IF 0.7 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-01-01 DOI:10.37360/blacpma.23.22.3.21

Gabriel Vargas-Arana, Elsa Rengifo-Salgado, M. Simirgiotis

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Abstract

Diabetes mellitus is a metabolic disorder characterized by the presence of chronic hyper-glycemia that is accompanied, to a greater or lesser extent, by alterations in the metabolism of carbohydrates, proteins and lipids. It is the leading cause of death in developed countries. Current antidiabetic drug treatments present several adverse effects for which it has started searching for new oral hypoglycemic agents from vegetal species. This review presents the medicinal plants from the Peruvian Amazon used in the treatment of diabetes and a systematic review of their hypoglycemic properties reported in the literature in the last twenty years used in different bibliographic databases. Seventy seven medicinal plants are reported as being used for the treatment of diabetes by Amazonian indigenous people, which 46.75% of species report hypoglycemic activity, evidencing that traditional knowledge is a great source for to searching antidiabetic drugs and also an alternative for future research.

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秘鲁亚马逊地区药用植物抗糖尿病潜力综述

糖尿病是一种代谢性疾病，以慢性高血糖为特征，并或多或少伴有碳水化合物、蛋白质和脂质代谢的改变。它是发达国家的主要死亡原因。目前的降糖药物治疗存在几种不良反应，已经开始从植物物种中寻找新的口服降糖药。本文综述了秘鲁亚马逊地区用于治疗糖尿病的药用植物，并系统回顾了近二十年来在不同文献数据库中报道的它们的降糖特性。据报道，亚马逊土著人用于治疗糖尿病的药用植物有77种，其中46.75%的植物具有降糖活性，这表明传统知识是寻找降糖药物的重要来源，也是未来研究的另一种选择。

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来源期刊

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas PHARMACOLOGY & PHARMACY-

CiteScore

1.30

自引率

14.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas (BLACPMA), [Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants]; currently edited by the publishing house MS-Editions, is a bi-monthly international publication that publishes original peerreviewed research in the field of medicinal and aromatic plants, with nearly 20 years of experience. BLACPMA is a scientific journal that publishes two types of articles: Reviews (only in English) and Original Articles (Spanish or English), its main lines of action being agronomy, anthropology and ethnobotany, industrial applications, botany, quality and standardization, ecology and biodiversity, pharmacology, phytochemistry, pharmacognosy, regulatory and legislative aspects. While all areas of medicinal plants are welcome and the experimental approaches used can be broad and interdisciplinary; other areas of research that are not mentioned depend on the Editorial Committee for their acceptance.