Biochemical and Toxicity Effects of Some 2-Benzoylpyridine Derivatives on Eobania vermiculata under Laboratory Conditions

Esam M. Emara, Maher El-Sawaf, Rashad Khalifa
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引用次数: 0

Abstract

Two derivatives of 2-Benzoylpyridine namely; (E)-4-((E)-4-((E)- phenyl(pyridin-2-yl)methyleneamino)benzyl)-N-(phenyl(pyridin-2-yl)methylene)benzenamine (L) and its Cu(II) complex were prepared and screened in vitro on Eobania vermiculata species. The assessment of LC 50 values of screened chemicals after 3 days of treatments was performed via the contact method. A series of four concentrations of the investigated compounds; (50, 150, 250, and 350 ppm) was prepared by using a mixture of distilled water and DMSO (3:1) by volume. The obtained results demonstrated that the tested snails were strongly affected after treatments with the prepared chemical compounds, which reflected the high toxicity of those compounds. LC 50 data of (E)-4-((E)-4-((E)-phenyl(pyridin-2-yl)
一些2-苯甲酰吡啶衍生物对蛭状绿钡的生化和毒性作用
2-苯甲酰吡啶的两个衍生物即;制备了(E)-4-((E)-4-(E)-苯基(吡啶-2-基)亚甲基氨基)苄基(L) - n-(苯基(吡啶-2-基)亚甲基)苯胺(L)及其Cu(II)配合物,并对其进行了体外筛选。通过接触法评估筛选的化学物质在处理3天后的lc50值。所研究化合物的一系列四种浓度;(50,150,250和350ppm)用蒸馏水和DMSO(3:1)的体积混合物制备。结果表明,所制备的化合物对钉螺的影响较大,反映了化合物的高毒性。LC 50数据(E) 4 - ((E) 4 - ((E)苯(pyridin-2-yl)
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