Anthelminthic activity of Asta Churna

Abstract

Purpose: To determine the effect of Asta churna (an ayurvedic preparation of Impcops) on Indian earthworms. Methods: Asta churna (2.5 mg/mL and 5 mg/mL) were investigated for activity in Indian earthworms (Pheretima postuma) against piperazine citrate (15 mg/mL) and albendazole (20 mg/mL) as standard references and normal saline as control. The time to achieve paralysis of the worms was determined. Results: The two concentrations of Asta churna exhibited significant anthelminthic activity (p < 0.001) when compared with the piperazine citrate, albendazole and normal saline. Conclusion: Asta chuma has paralytic effect on Indian earthworms. Keywords: Asta churna, Pheretima postuma, Anthelminthic activity