The Anti-Fatigue Effect in Skeletal Muscle Model Rats of Odorless Garlic Extract.

Abstract

709-0716, Japan Abstract The anti-fatigue properties of odorless garlic extract (OGE) were investigated by monitoring the recovery rate from muscular fatigue in anesthetized rats. In the experiment, muscular fatigue was induced by applying rapid electric stimulations to the skeletal muscle. Fatigue recovery rates were measured after a 60- and a 90-minute interval in the treated group and the control group, respectively. The results indicated that OGE had a certain degree of anti-fatigue effect (p<0.1) in the treated group (1g/kg/day oral administration of OGE for 14days). No significant body weight change in either group was observed during the experiment period, suggesting that OGE is safe at the dosage