Abstract PO-094: Gα13 loss in KPC mouse model promotes well-differentiated pancreatic tumors that are susceptible to mTOR inhibition

IF 7.3 1区生物学

Science Signaling Pub Date : 2021-11-15 DOI:10.1158/1538-7445.panca21-po-094

M. Shields, Christina Spaulding, Mahmoud G. Khalafalla, Thao N. D. Pham, H. Munshi

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摘要PO-094: Gα13缺失在KPC小鼠模型中促进了易受mTOR抑制的胰腺高分化肿瘤

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来源期刊

Science Signaling Biochemistry, Genetics and Molecular Biology-Molecular Biology

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148

期刊介绍： Science Signaling is a weekly, online multidisciplinary journal dedicated to the life sciences. Our editorial team's mission is to publish studies that elucidate the fundamental mechanisms underlying biological processes across various organisms. We prioritize research that offers novel insights into physiology, elucidates aberrant mechanisms leading to disease, identifies potential therapeutic targets and strategies, and characterizes the effects of drugs both in vitro and in vivo.