The Influence of Process Energy on the Yield of Asymmetric Curcumin Analog from Cullilawan Oil

Abstract

Asymmetric curcumin analogue compound is an anticancer compound synthesized from cullilawan oil with several stages of the process such as; Isolation of safrol from cullilawan oil, safol isomerisation, oxidation, intermediate product synthesis and asymmetric curcumin analog synthesis. The amount of energy used for asymmetric curcumin analog synthesis process gives effect to yield. The purpose of this research is to know the effect of process energy on asymmetric curcumin analogue yield from lawang oil. The results of the study showed that the synthesis of curcumin analogue compounds using microwave method on different energy quantities (8.4kJ, 25.2 kJ, 33.6 kJ, 75 kJ) gives effect to yield. The greater the energy used in the process will lower the yield and the energy that gives the highest yield is 8.4 kJ.