Phytochemical Analysis, Cytotoxcity and Antifungal Activities of Guiera Senegalensis Leaves Extract Review

Abstract

The aim of this review is to investigate the phytochemical analysis, toxicity, and the antifungal activity of Gueira senegalensis leaves extract and compare methods. Extract of the leaves of Gueira senegalensis was tested for its antimicrobial activity against Stemphylium solani, Aspergillus flavus, Trichoderma viride, Penicillium Spp., Fusarium verticillatum, Cladosporium cladosporioides, and Fusarium solani. This review showed that Gueira senegalensis leaves extract has no inhibition activity against all of the tested fungal strains. On the other hand, the toxicity test, which was conducted by using brine shrimp, suggests that Gs leaves extract is apparently not toxic. The phytochemical screening revealed that Gueira senegalensis leave extract contains alkaloids, flavonoids, terpenoids, tannin, carbohydrates, proteins, steroids, and saponins. The results of this preliminary investigation suggest that the medicinal plant extract may be safe to use as a drink for treatment of various diseases as has been practiced for years in the villages of Western Sudan. More research is needed to investigate if there is any side effect when the extract is taken orally. Further, the medicinal properties of the phytochemical compounds of Gueira senegalensis need to be further investigation.