Role of Combination Therapy in Relapsed Ewing’s Sarcoma

Abstract

Ewing's Sarcoma has increased chances of relapsing and metastases with deposits of lesions in other bones and organs. Its peak occurrence is between the age group of 10 to 20 years affecting the elderly too. We present a case on Relapsing of Ewing's Sarcoma in the right finger and metastases to the left knee joint. The PET CT initially revealed a small metabolically active lesion in the lateral aspect of the base of the right ring finger. With recurrence of chief complaint, PET CT image, MRI scan, and other confirmative procedures he was confirmed with RES. He was followed by a chemotherapy protocol of VAC/IE in 17 cycles, radiation therapy and additional therapy. Our patient showed improvement in his side effects with immunotherapy for his hair loss. He did not undergo any surgical procedures. Appropriate patient counselling and discharge medications with time to time reviewing were carried out in the patient. This case elaborates the benefits of combination therapy in an RES when compared to chemotherapy alone.