Kidney transplantation in children and young adults: the initial experience of our center

U. Ozgen, Murat Özban, İ. H. Akbudak, Selcuk Yuksel, İ. Gi̇ri̇şgen, M. Aykota, E. Mete, Neslihan Yilmaz, Ezgi Doğa Yoran, Osman Uzunlu, Mevlüt Çeri̇, O. Birsen, Çağatay Aydin
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Abstract

Abstract Purpose: Pediatric kidney transplant (PKTx) is one of the most comfortable renal replacement therapies preferred in children with end-stage renal disease (ESRD) worldwide. Methods: This single-center, retrospective study was conducted at Pamukkale University, Faculty of Medicine, Organ Transplantation Center. The PKTx was performed in 11 patients between December 2014 and November 2019. Results: The mean time from the beginning of the first dialysis session to transplantation was 40.2 months, and two patients were transplanted preemptively. The mean age of LD and DD transplants was 41.6 years and 17.1 years, respectively. This was attributed to the fact that, in the donation of cadaveric organs, donors under the age of 18 years are only registered for the waiting list for the recipients under the age of 18 years in our country. Conclusion: Our study showed that patients who used basiliximab for induction treatment were more advantageous in terms of infections than patients using ATG.
儿童和青少年肾移植:本中心的初步经验
摘要目的:儿童肾脏移植(PKTx)是世界范围内终末期肾病(ESRD)儿童最舒适的肾脏替代疗法之一。方法:单中心回顾性研究在Pamukkale大学医学院器官移植中心进行。在2014年12月至2019年11月期间对11名患者进行了PKTx。结果:从第一次透析开始到移植平均时间为40.2个月,2例患者提前移植。LD和DD移植的平均年龄分别为41.6岁和17.1岁。这是由于在捐献尸体器官时,18岁以下的捐献者只登记在我国18岁以下受赠人的等候名单上。结论:我们的研究表明,使用basiliximab进行诱导治疗的患者在感染方面比使用ATG的患者更有利。
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