Amifampridines (3,4 Diaminopyridine and 3,4 Diaminopyridine Phosphate): Drugs of Choice for Lambert-Eaton Myasthenic Syndrome

Shin J Oh
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Abstract

Amifampridines have been known to be effective as symptomatic treatment of Lambert-Eaton myasthenic syndrome since 1983. Food Drug Administration (FDA) approved amifampridines, the most studied safe and effective drugs in the neuromuscular diseases, are available for the general use for symptomatic treatment of LEMS, 60 years after the first description of LEMS and 40 years after the first trial of 3,4-DAP in LEMS.
氨苯丙啶(3,4二氨基吡啶和3,4磷酸二氨基吡啶):兰伯特-伊顿肌无力综合征的首选药物
自1983年以来,阿米福定被认为是有效的兰伯特-伊顿肌无力综合征的对症治疗。amifampri定是美国食品药品监督管理局(FDA)批准的神经肌肉疾病中研究最多的安全有效的药物,在LEMS首次描述60年后,在3,4- dap在LEMS中的首次试验40年后,可用于LEMS的一般对症治疗。
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