Effect of Vitamin A and Vitamin E on Serum Cholesterol and Atherosclerosis in the Hen

Abstract

Hens (2-years-1-month old) fed a diet containing 10% of grease and 0.5% of cholesterol developed atherosclerotic lesion in 8 months. Vitamin A (10mg of vitamin A acetate/day/hen) or vitamin E (50 mg of dl-α-tocopherol acetate/day/hen) administered singly or together seemed to decrease serum cholesterol and cholesterol esters in the aortic lipids even though this effect was not significant because of large variations within the group. No synergistic action of two vitamins was not observed. The excretion of lipid in the feces was increased by the addition of the vitamins.