Postcovid Syndrome and Chronic Heart Failure: Current Issues

D. Gamayunov, A. Kalyagin, G. Sinkova, O. Ryzhkova, Y. Varavko
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Abstract

Objective of the Review: To consider the pathogenetic relationship of COVID-19 and chronic heart failure, the concept of “postcovid syndrome”, the peculiarities of management of this group of patients. Key points. Chronic heart failure is a predictor of an unfavorable outcome in patients with COVID-19. Angiotensin converting enzyme 2 is involved in the penetration of viral particles into the cell. Direct viral damage to cardiomyocytes is not excluded, cardiotoxic effects of antiviral therapy are possible. The consequences of COVID-19 are manifested by arrhythmia, myocarditis and pericarditis, cardiomyopathy. Corticosteroids can lead to decompensation of heart failure. The use of renin-angiotensin-aldosterone system inhibitors and β-blockers is associated with lower mortality. Conclusion. Chronic heart failure in combination with postcovid syndrome requires carefully developed patient management tactics and rehabilitation measures. Keywords: chronic heart failure, postcovid syndrome, COVID-19.
covid后综合征和慢性心力衰竭:当前问题
综述目的:探讨新冠肺炎与慢性心力衰竭的发病关系、“冠后综合征”的概念以及这类患者的治疗特点。要点。慢性心力衰竭是COVID-19患者不良结果的预测因子。血管紧张素转化酶2参与了病毒颗粒渗透到细胞中的过程。不排除病毒对心肌细胞的直接损伤,抗病毒治疗的心脏毒性作用是可能的。COVID-19的后果表现为心律失常、心肌炎和心包炎、心肌病。皮质类固醇可导致心力衰竭失代偿。肾素-血管紧张素-醛固酮系统抑制剂和β-阻滞剂的使用与较低的死亡率相关。结论。慢性心力衰竭合并covid后综合征需要精心制定患者管理策略和康复措施。关键词:慢性心力衰竭,冠后综合征,COVID-19
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