Analyzing the Impact of the Substituent on the Quinazolinone Schiff Base and the Interaction of the Fe (III) and Cr (III) with Different Quinazolinone Schiff Base for Antioxidant and Anti-inflammatory Activity

Abstract

Abstract Schiff base and their Fe (III), Cr (III) complexes stood vetted for Antioxidant, Anti-inflammatory activities and docking study. Mixed ligand complexes had strong antioxidant and anti-inflammatory properties. Docking study of mixed ligand complexes reveals substantial binding affinity for COX2 and STAT3 receptors. The experimental and computational anti-inflammatory and antioxidant activity results are more consistent. GRAPHICAL ABSTRACT