DEVELOPMENT OF AN HPLC METHOD FOR SIBUTRAMINE IDENTIFICATION. SEARCH FOR UNDECLARED SIBUTRAMINE IN BIOLOGICALLY ACTIVE ADDITIVES APPETITE SUPPRESSANTS

Ruben E. Israyelyan, T. Sargsyan
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Abstract

In this study an available reversed-phase HPLC method for the identification of sibutramine with UV detection and isocratic elution mode was developed, the evaluation of the method applicability and determination of validation indicators were carried out. It has been shown that the developed method meets the current international requirements. To search for sibutramine, the developed method has been used in some biologically active additives ("Lipocarnit", "Pineapple extract", "Turboslim night" and "Turboslim day").
西布曲明HPLC鉴别方法的建立。在生物活性添加剂食欲抑制剂中寻找未申报的西布曲明
本研究建立了一种适用于西布曲明的反相高效液相色谱法,采用紫外检测和等密度洗脱模式,对方法的适用性进行了评价,并对验证指标进行了确定。实践表明,所开发的方法符合当前国际上的要求。为了寻找西布曲明,所开发的方法已用于一些生物活性添加剂(“Lipocarnit”,“菠萝提取物”,“Turboslim night”和“Turboslim day”)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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