Analysis of risk factors of perinatal pathology in newborns with congenital defects

Abstract

Newborns with congenital defects usually have a burdened perinatal history, and their mothers' pregnancy proceeds against the background of severe complications and exacerbation of chronic pathology. In modern obstetrics, many indicative scales are used to determine the degree of risk of perinatal and maternal pathology, including a point assessment on the Coopland scale. The aim. Conduct a clinical and epidemiological analysis of perinatal and maternal risk factors according to the A. Coopland scale and analyze the frequency of perinatal pathology in newborns with congenital defects in the early neonatal period. Materials and methods. We retrospectively and selectively analyzed 88 birth histories of mothers of newborns with congenital malformations who received surgical treatment in the neonatal center and scored risk factors for perinatal and maternal pathology according to the A. Coopland scale. Results. It was revealed that mothers of newborns with congenital defects were included in the groups of high (3–6 points) and very high (7 or more) predicted risk of perinatal and maternal pathology. The high-risk group included 28 (32 %) mothers, and 60 women (68 %) the very high-risk group of perinatal and maternal pathology. Conclusions. In women with more than 15 points on the A. Coopland scale 4.7 times more often children were born with intrauterine infection, gastrointestinal disorders, NEC and severe respiratory disorders in the early neonatal period compared with mothers who gave birth to newborns with the same gestational age and a group of low and high risk of perinatal and maternal pathology