Letter to the Editor: Genetic Editing of Secretory Pathway of Penicillium Chrysogenum After Observation of Increased Secretory Rates in an Increased Stress Environment (Microgravity), a Research Proposal by High School Students in Dubai

Fine focus Pub Date : 2018-12-21 DOI:10.33043/FF.4.2.163-169
A. Shirali, Wilson Minter Huijsmans, M. Sottocornola
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引用次数: 1

Abstract

In this study, we aim to amplify the secretory pathway of Penicillium Chrysogenum within the ISS or similar simulated microgravity using the miniPCR and/or RTQ-PCR and then optimizing Penicillium Chrysogenum function using CRISPR cas-9 (Clustered Regularly Interspaced Short Palindromic Repeats), a new technology in the genetics which can help in gene alteration for better drug production. The secretory pathway of Penicillium Chrysogenum is controlled by genes pcbAB , pcbC and penDE
致编辑的信:在增加应激环境(微重力)下观察到分泌率增加后对青霉菌分泌途径的基因编辑,迪拜高中生的研究提案
在这项研究中,我们的目标是利用miniPCR和/或RTQ-PCR扩增青霉菌在ISS或类似的模拟微重力下的分泌途径,然后利用CRISPR cas-9 (Clustered Regularly Interspaced Short Palindromic Repeats)优化青霉菌的功能,这是遗传学中的一项新技术,可以帮助基因改变以更好地生产药物。青霉菌的分泌途径受pcbAB、pcbC和penDE基因控制
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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