Hsun-Hua Lee, Chih-Chung Chen, J. Ong, Yuan-Feng Lin, F. Lee, Chaur-Jong Hu, Yuan-Hung Wang
{"title":"Association of rs2651899 Polymorphism in the Positive Regulatory Domain 16 and Common Migraine Subtypes: A Meta‐Analysis","authors":"Hsun-Hua Lee, Chih-Chung Chen, J. Ong, Yuan-Feng Lin, F. Lee, Chaur-Jong Hu, Yuan-Hung Wang","doi":"10.1111/head.13670","DOIUrl":null,"url":null,"abstract":"Migraine is a neurovascular disease with recurrent headache attacks. A polymorphism (rs2651899) of the PRDM16 gene, which is associated with migraine, was identified in recent genome‐wide association studies. The potential role of the PRDM16 rs2651899 polymorphism in migraine is still unknown. Therefore, we conducted this systematic review and meta‐analysis to examine this issue.","PeriodicalId":12845,"journal":{"name":"Headache: The Journal of Head and Face Pain","volume":"58 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Headache: The Journal of Head and Face Pain","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/head.13670","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Migraine is a neurovascular disease with recurrent headache attacks. A polymorphism (rs2651899) of the PRDM16 gene, which is associated with migraine, was identified in recent genome‐wide association studies. The potential role of the PRDM16 rs2651899 polymorphism in migraine is still unknown. Therefore, we conducted this systematic review and meta‐analysis to examine this issue.