On the preparation of 3-(5-Formyl-3-thioxo-3H-[1,2]dithiol-4-yl)-propionic acid

Abstract

3-(5-Formyl-3-thioxo-3H-[1,2]dithiol-4-yl)propionic acid has been obtained from 3-[5-(hydroxyiminomethyl)-3-thioxo-3H-[1,2]dithiol-4-yl]propionic acid under standard conditions. Conversely, for the hydroxyimino derivative the general procedure failed and so it has been prepared by the action, in a basic medium, of isoamyl nitrite on 3-(5-methyl-3-thioxo-3H-[1,2]dithiol-4-yl)propionic acid ethyl ester.