Chemometrics and infrared spectroscopy – A winning team for the analysis of illicit drug products

IF 3.6 3区化学 Q2 CHEMISTRY, ANALYTICAL

Reviews in Analytical Chemistry Pub Date : 2022-01-01 DOI:10.1515/revac-2022-0046

E. Deconinck, Céline Duchateau, Margot Balcaen, L. Gremeaux, P. Courselle

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引用次数: 3

Abstract

Abstract Spectroscopic techniques such as infrared spectroscopy and Raman spectroscopy are used for a long time in the context of the analysis of illicit drugs, and their use is increasing due to the development of more performant portable devices and easy application in the context of harm reduction through drug checking or onsite forensic analysis. Although these instruments are routinely used with a spectral library, the importance of chemometric techniques to extract relevant information and give a full characterisation of samples, especially in the context of adulteration, is increasing. This review gives an overview of the applications described in the context of the analysis of illicit drug products exploiting the advantages of the combination of spectroscopy with chemometrics. Next to an overview of the literature, the review also tries to emphasize the shortcomings of the presented research papers and to give an incentive to what is needed to include chemometrics as a part of the daily routine of drug checking services and mobile forensic applications.

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化学计量学及红外线光谱学-分析违禁药物的优胜队伍

红外光谱和拉曼光谱等光谱技术在非法药物分析中应用已久，由于性能更高性能的便携式设备的发展以及易于通过药物检查或现场法医分析减少危害的背景下，其使用量正在增加。虽然这些仪器通常与光谱库一起使用，但化学计量技术在提取相关信息和给出样品的完整特征方面的重要性正在增加，特别是在掺假的情况下。本文综述了利用光谱学与化学计量学相结合的优点在非法药物分析方面的应用。除了对文献的概述之外，该综述还试图强调所提出的研究论文的缺点，并鼓励将化学计量学作为药物检查服务和移动法医应用的日常工作的一部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reviews in Analytical Chemistry 化学-分析化学

CiteScore

7.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Reviews in Analytical Chemistry publishes authoritative reviews by leading experts in the dynamic field of chemical analysis. The subjects can encompass all branches of modern analytical chemistry such as spectroscopy, chromatography, mass spectrometry, electrochemistry and trace analysis and their applications to areas such as environmental control, pharmaceutical industry, automation and other relevant areas. Review articles bring the expert up to date in a concise manner and provide researchers an overview of new techniques and methods.