A Case Report of Colon Cancer Succeeding Long Survival Without Chemotherapy, Msi-H, Braf Mutated

Maria-Theodora Papadimitriou, D. Symeonidis, Alexandros-Nikolaos, Liatsos, S. Xynogalos
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Abstract

Immunotherapy is now indicated in the first line setting in metastatic colon cancer, while it is generally indicated in MSI-H tumors. A similar BRAFm V600E mutation is a poor prognostic indicator, while there is approved treatment in the 2nd line. The tolerance profile of these treatments may be the same or even better compared to chemotherapy and their use has gained considerable priority. The aim with this report is to highlight the possibility of successfully treating a patient with metastatic colon cancer without chemotherapy in the first two lines, especially when it ought to a frail patient. The patient is monitored in our department from the beginning of her diagnosis until the moment of this publication.
无化疗、Msi-H、Braf突变的结肠癌长期存活1例
免疫治疗现在被用于转移性结肠癌的一线治疗,而它通常被用于MSI-H肿瘤。类似的BRAFm V600E突变是一个不良的预后指标,而在二线有批准的治疗。与化疗相比,这些治疗的耐受性可能相同甚至更好,因此它们的使用得到了相当大的优先考虑。本报告的目的是强调成功治疗转移性结肠癌患者的可能性,特别是当它应该是一个虚弱的病人。从诊断开始到本文发表,患者在我科接受监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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