The Effect of Ganoderma Lucidum Powder on some Immune Parameters in Rat

Hiyam Altai, Mahmood A. A. Altobje, Ali J. Dawood
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引用次数: 1

Abstract

Ali A. Dawood aad@uomosul.edu.iq ABSTRACT The impact of Ganoderma lucidum powder on both chemokines, IgG and C3 complement concentrations, as well as WBC types, was investigated in 60 ester citrine rats split between two groups, one of which was injected with Carbon tetrachloride CcL4 and the other with Ganoderma lucidum powder. They were not given this drug; instead, two concentrations of mushroom powder, 40 mg/ per kilo-gram of body weight and 80 mg/ per kilo gram of body weight, were utilized, along with a control group. The results revealed a clear increase in all immune factors measured, with a clear difference between males and females when compared to control samples, as well as an increase in the numbers of both neutrophils and lymphocytes in males for both concentrations, with a higher increase for the second concentration than the first, while the increase in females for both concentrations was similar. In the groups exposed to CcL4, an increase in the values of chemokines, IgG, and C3 as well as the number of neutrophils appeared in males in varying numbers for both concentrations, whereas the increase in females appeared in the second concentration higher than the first concentration of immune values, and the opposite was true for the number of white cells. The number of monocytes showed slight changes in both males and females under study with clear significant differences between C3, chemokine, white blood cell count, lymphocytes and monocytes.
灵芝粉对大鼠免疫指标的影响
摘要以60只柠檬酸酯大鼠为实验对象,研究了灵芝粉对趋化因子、IgG和C3补体浓度以及白细胞类型的影响,并将其分为两组,分别注射四氯化碳CcL4和灵芝粉。他们没有服用这种药物;取而代之的是,使用了两种浓度的蘑菇粉,每公斤体重40毫克和每公斤体重80毫克,以及一个对照组。结果显示,所有测量的免疫因子都明显增加,与对照样品相比,男性和女性之间存在明显差异,两种浓度下男性中性粒细胞和淋巴细胞的数量都有所增加,第二种浓度的增加幅度高于第一种浓度,而两种浓度下女性的增加幅度相似。在暴露于CcL4的组中,雄性趋化因子、IgG和C3的值以及中性粒细胞的数量在两种浓度下都有不同数量的增加,而雌性在第二种浓度下的增加高于第一种浓度的免疫值,白细胞的数量则相反。在研究中,男性和女性的单核细胞数量变化不大,C3、趋化因子、白细胞计数、淋巴细胞和单核细胞之间存在明显的显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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