EVALUATION OF WOUND HEALING ACTIVITY OF POLYHERBAL GEL FORMULATION

Amrapali S. Kakade
{"title":"EVALUATION OF WOUND HEALING ACTIVITY OF POLYHERBAL GEL FORMULATION","authors":"Amrapali S. Kakade","doi":"10.20959/WJPR201710-8982","DOIUrl":null,"url":null,"abstract":"The aim of present study was Evaluation of Wound Healing activity of Polyherbal Gel Formulation. The different concentration of gel was prepared by using corbopol 940 as a gel base. Azadirachta Indica leaves extract, Tridax procumbens leaves extract, and honey by using partial thickness burn wound model in winster rats. All animals were divided into six groups. Group I was control, Group II was treated by 1% of Azadirachta Indica gel, Group III was treated by 1% of Tridax procumbens gel, Group IV were treated by 1% Honey gel . Group V were treated by polyherbal gel and Group IV were treated by Marketed Preparetion (Reference Standard). For 15 days all gel applied topically. The wound healing activity evaluated by physical parameters namely wound contraction and epithelialization. The polyherbal gel shows significant effect on wound healing activity.","PeriodicalId":23796,"journal":{"name":"World journal of pharmaceutical research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of pharmaceutical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20959/WJPR201710-8982","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

Abstract

The aim of present study was Evaluation of Wound Healing activity of Polyherbal Gel Formulation. The different concentration of gel was prepared by using corbopol 940 as a gel base. Azadirachta Indica leaves extract, Tridax procumbens leaves extract, and honey by using partial thickness burn wound model in winster rats. All animals were divided into six groups. Group I was control, Group II was treated by 1% of Azadirachta Indica gel, Group III was treated by 1% of Tridax procumbens gel, Group IV were treated by 1% Honey gel . Group V were treated by polyherbal gel and Group IV were treated by Marketed Preparetion (Reference Standard). For 15 days all gel applied topically. The wound healing activity evaluated by physical parameters namely wound contraction and epithelialization. The polyherbal gel shows significant effect on wound healing activity.
多草药凝胶制剂创面愈合活性的评价
本研究的目的是评价复方凝胶制剂的创面愈合活性。以corboopol 940为凝胶基质制备不同浓度的凝胶。印楝叶提取物、三叶提取物和蜂蜜对冬季大鼠部分厚度烧伤模型的影响。所有的动物被分成六组。ⅰ组为对照组,ⅱ组为1%印楝凝胶,ⅲ组为1%原甘油三酯凝胶,ⅳ组为1%蜂蜜凝胶。V组用多草药凝胶治疗,IV组用市售制剂(参考标准)治疗。15天,所有凝胶局部应用。创面愈合活性评估的物理参数,即创面收缩和上皮化。该复方凝胶对伤口愈合活性有显著的促进作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信