Impact of Stress and Trait Anxiety on the Sensory and Jaw Motor Responses to a Tonic Orofacial Nociceptive Stimulus.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-12-01 DOI:10.11607/ofph.3048

Jeffrey Cf Chow, Paolo Chiodini, Ambra Michelotti, Richard Ohrbach, Iacopo Cioffi

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引用次数: 1

Abstract

Aims: To investigate how trait anxiety and stress jointly affect the sensory and jaw motor responses to a tonic orofacial nociceptive stimulus.

Methods: Orthodontic separators were placed between the first molars in 45 adults with low (n = 14), intermediate (n = 17), and high (n = 14) trait anxiety. Tooth pain, occlusal discomfort, tooth clenching (as a jaw motor behavior), and situational stress were measured three times a day for 5 days using visual analog scales. Mixed-effects regression models were used to evaluate the sensory and motor outcome measures.

Results: Pain, discomfort, and frequency of tooth-clenching trajectories were affected by trait anxiety (P = .007, P < .001, and P = .055, respectively) and stress (P < .001, P < .001, and P = .044, respectively). Individuals with high anxiety reported their highest pain (17.7 ± 2.9 mm) and discomfort (35.2 ± 4.1 mm) 24 hours earlier than those with low anxiety (pain: 15.9 ± 2.6 mm, discomfort: 28.8 ± 3.7 mm). Tooth clenching decreased progressively in response to the stimulus (P < .001).

Conclusion: A tonic orofacial nociceptive stimulus triggers an avoidance jaw motor behavior. Both trait anxiety and situational stress heighten the sensory response to such a stimulus, but weakly affect the motor response to it.

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应激和特质焦虑对强直性口面部伤害性刺激的感觉和颌运动反应的影响。

目的:探讨特质焦虑和应激如何共同影响对强直性口面部伤害性刺激的感觉和颌运动反应。方法:对45例低(n = 14)、中(n = 17)、高(n = 14)特质焦虑患者的第一磨牙间放置正畸分离器。使用视觉模拟量表测量牙痛、咬合不适、咬牙紧咬(作为颌运动行为)和情境应激，每天3次，持续5天。使用混合效应回归模型评估感觉和运动结果测量。结果:特质焦虑(P = .007, P < .001, P = .055)和应激(P < .001, P < .001, P = .044)对牙痛、不适和咬牙轨迹频率均有影响。高焦虑组疼痛(17.7±2.9 mm)和不适感(35.2±4.1 mm)比低焦虑组(15.9±2.6 mm, 28.8±3.7 mm)早24小时。紧牙现象随刺激的增加而逐渐减少(P < 0.001)。结论:强直性口面部伤害性刺激可诱发逃避性颌运动行为。特质焦虑和情境应激都能增强对这种刺激的感觉反应，但对运动反应的影响较弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.