P5B-12 How Do Conservation Laws Define a Motion Suppression Score in In-Vivo Ivus Sequences?

Abstract

Evaluation of arterial tissue biomechanics for diagnosis and treatment of cardiovascular diseases is an active research field in the biomedical imaging processing area. Intravascular UltraSound (IVUS) is a unique tool for such assessment since it reflects tissue morphology and deformation. A proper quantification and visualization of both properties is hindered by vessel structures misalignments introduced by cardiac dynamics. This has encouraged development of IVUS motion compensation techniques. However, there is a lack of an objective evaluation of motion reduction ensuring a reliable clinical application This work reports a novel score, the Conservation of Density Rate (CDR), for validation of motion compensation in in-vivo pullbacks. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases.