Research Progress of the Relationship between Uric Acid and Disease

Abstract

Uric acid is the end product of purine metabolism. It will cause physical pain and impaired function when the blood concentration exceeds a certain threshold. It is acknowledged that hyperuricemia is related to cardiovascular disease, metabolic syndrome, stroke and kidney disease. However, there is no consensus on the relationship between uric acid and different diseases and whether uric acid is an independent risk factor of these diseases. This article reviews the rela-