Evaluation of PcsB as Potential Vaccine Candidate Using Computational Tools

Abstract

Streptococcus agalactiae/GBS is an organism that is responsible for many severe infections in infants as well as in adults. Streptococcus Agalactiae is a gram-positive bacterium that causes pneumonia, sepsis, and meningitis in newborns, as well as infections of the bones and joints [1]. Subclinical mastitis in dairy cattle is commonly caused by Streptococcus Agalactiae. It's a mammary parasite that can be treated with a variety of antibiotics. In this study a bioinformatics tool was used to find out if PcsB can be a good vaccine candidate to combat the disease. If according to results the desired protein can be a good vaccine candidate then it can be studied further.