Review on the Synthesis of α-Aminophosphonate Derivatives

Abstract

α-Aminophosphonates are bioesters of amino acids and have several pharmacological activities. The high therapeutic properties of these compounds have encouraged researchers to synthesize new α-aminophosponate derivatives by Kabachnik field reaction and by Pudovik reaction by using different catalyst, under microwave irradiation, sonication etc. This article aims to review the work reported by researchers under different conditions and their biological activities.