Quantitative evaluation of rabbit's hepatic function by HEF, DISADA-K, and ICG R/sub max/ methods

Abstract

The hepatic extraction fraction (HEF), DISIDA-K, and ICG R/sub max/ were obtained to evaluate hepatic function for two normal and four abnormal rabbits with rapidly damaged livers. The correlation coefficients among these three methods were found. The correlation coefficient between the HEF and ICG R/sub max/ which is a standard technique in evaluating hepatic function was found to be 0.93. Therefore the HEF is assumed to be a valuable diagnostic method since it is not only accurate and simple, but possible to estimate remaining hepatic function after surgical removal of cancerous hepatic tissues.