Constructing Method of the Functional Network of Activating Blood and Dissolving Stasis

Wang Yun, Wang Gang, Xiao Bin, Qiao Yanjiang
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Abstract

The mechanism of Chinese herbal medicine remains unrevealed because we know little about the interacting targets of its constituents. Taking the function of “Activating Blood and Dissolving Stasis” (ABDS) as an example, a method to construct a functional network is proposed, and the functional network of ABDS is established. The results indicate that this method can not only establish a theoretical basis for explaining the mechanism of Chinese herbal medicine, but also provide new clues for the clinical treatment of complex diseases and drug development. This method may serve as a practical solution to functional network construction.

活血化瘀功能网络的构建方法
中草药的作用机制尚不清楚,因为我们对其成分的相互作用靶点知之甚少。以活血化瘀(ABDS)功能为例,提出了一种构建功能网络的方法,并建立了ABDS功能网络。结果表明,该方法不仅可以为解释中草药作用机理奠定理论基础,而且可以为复杂疾病的临床治疗和药物开发提供新的线索。该方法可作为功能网络构建的实用解决方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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