MULTICENTRIC AND BILATERAL APPEARANCE OF LOBULAR CARCINOMA IN SITU OF THE BREAST

Abstract

During a follow-up period averaging 17 years (2–30 years), 64 breast tissue specimens were removed in 52 females with lobular carcinoma in situ of the breast (LCIS) before, simultaneous with or subsequent to the detection of LCIS. In 8 out of 25 cases the LCIS was bilateral, and in 9 out of 19 it was multicentric. The present study does not reveal the actual multicentric and bilateral appearance of LCIS, but the “spontaneous” appearance in a series of specimens which were not removed or investigated primarily with the object of detecting this breast disease.