RAPID DISSOLVE ORAL DOSAGE FORMS- A DETAIL REVIEW

Abstract

In the current scenario of novel drug delivery system, much emphasis has been given to effective dosage form in term of producing steady level concentration in plasma for controlled release drug delivery system and rapid release drug for quick effects. In case of allergy, chemotherapeutics side effect treatment, pain medicines and pediatric as well as geriatrics drug delivery prefers rapid response of drug. Numbers of drug from above categories have been formulated in rapid release tablet or film. With the use of natural polymers and superdisintegrants it is feasible to prepare these dosage forms to dissolve within 1min with minimum quantity of water. The aim of present review is to give complete detailed including all formulation aspects and evaluation parameters of rapid dissolve tablets and films. This review is first of its kind, as per our knowledge, which compiles complete information in one article. Rapid dissolve formulation have very high acceptance rate due to patient friendly formulation. Several technologies have been developed and patented. This review also covers patented technology.