BACTERIAL INVASION AS A KEY FACTOR IN PROGRESSION OF REACTIVE ARTHRITIS ON EXAMPLE OF CLINICAL CASE

Abstract

A clinical case of middle age male diagnosed with reactive arthritis developed on the background of multiple bacterial invasions such as Salmonella enterica, Ureaplasma urealyticum, Mycoplasma hominis, Borrelia burgdorferi sensu lato and characterized by chronic persistent course of the disease with destructive-inflammatory changes in the joints. This case illustrates the influence of bacterial pathogens on the course and the progression of reactive arthritis. In our patient, reactive arthritis was charac-terized by a chronic persistent course with a constant increase in inflammatory markers and destructive-inflammatory changes in the joints.An important role in the progression of reactive arthritis in this patient played multiple bacterial invasions, which were not only a trigger of the onset of the disease, but also maintained a chronicity of the pathological processes.This clinical case is an illustration of the fact that infectious bacterial diseases play a key role in the pathogenesis of reactive arthritis, and repeated bacterial infections affect the course and progression of the disease, which leads to a significant disruption of the functionof the musculoskeletal system.It is important to treat the patient with avoidance of polypharmacy; this goal is achieved by the appointment of several basic drugs and a supportive therapy used in courses.