Protective Effects of Wheat Germ Oil on the IVF, Oxidative Stress and In Vitro Zygote Development in Carbamazepine Treated Epileptic Male Mice

Abstract

Received: 27 Nov,2019 Accepted: 10 Feb, 2020 Abstract Background and Objectives: Epilepsy is a neurological disorder caused by abnormal electrical discharges from the brain. Carbamazepine is used to treat epilepsy.Over time, this drug may increase oxidative stress and reproductive abnormalities in patients with epilepsy. Wheat germ oil has the highest amount of vitamin E, among other vegetable oils. The aim of this study was to evaluate the effect of wheat germ oil as an antioxidant-rich source on oxidative stress and in vitro fertilization in carbamazepine-treated epileptic male mice.