Keratoacanthoma seen with hidradenitis suppurativa: A case report

IF 0.1 Q4 DERMATOLOGY
A. Bilgic, Kifayat Mammadli, C. Başsorgun, E. Alpsoy
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引用次数: 0

Abstract

Hidradenitis suppurativa (HS) is considered a primary disease of the hair follicle. The chronic occlusion of the follicular pilosebaceous unit and an associated immune response appears to be the main causes. The chronic, active, and poorly controlled disease may lead to several complications such as scars, contractures, lymphedema, osteomyelitis, and squamous cell carcinoma (SCC). We report here a 33-year-old male with HS who developed keratoacanthoma while on secukinumab treatment. The tumor representing 2 weeks of evolution in an area affected by HS (lower abdomen) was followed up after histopathological confirmation. Almost complete spontaneous regression was observed at the subsequent visits. As far as we are aware, solitary keratoacanthoma associated with HS has not been previously described. Our case shows that squamous differentiation is not limited to SCC and can develop from any scar tissue outside the anogenital region in patients with HS. Thus, the case presented here emphasizes the necessity of careful examination in scar areas as well as inflammatory lesions in HS.
角棘瘤合并化脓性汗腺炎1例
化脓性汗腺炎(HS)被认为是毛囊的原发性疾病。毛囊皮脂腺单位的慢性闭塞和相关的免疫反应似乎是主要原因。慢性、活动性和控制不良的疾病可能导致一些并发症,如疤痕、挛缩、淋巴水肿、骨髓炎和鳞状细胞癌(SCC)。我们在此报告一位33岁男性HS患者,在接受secukinumab治疗时发生了角棘瘤。在组织病理学证实后,对HS影响区域(下腹)的肿瘤进行了2周的随访。在随后的访问中观察到几乎完全的自发消退。据我们所知,与HS相关的孤立性角棘瘤以前没有被描述过。我们的病例表明鳞状分化不仅限于鳞状细胞癌,而且可以在HS患者的肛门生殖器区域以外的任何疤痕组织中发展。因此,这里的病例强调了在HS的疤痕区域和炎症病变中仔细检查的必要性。
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CiteScore
0.50
自引率
0.00%
发文量
13
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