Method to Produce Curcumin Oil-in-Water Nanoemulsions as Templates for Drug Carriers

Abstract

Curcumin has a wide spectrum of biological and pharmacological activities, which could be better exploited in numerous medical applications if it were not for its poor water-solubility. In this study, we describe a new method to improve curcumin solubility, using a combination of paraffin oil and ethanol. Further, we describe a systematic and efficient procedure to develop a formulation and a scalable mixing method in order to produce curcumin loaded oilin- water nanoemulsions that can be used as nanocapsule templates with potential biomedical applications.