CHAPTER 10. Noncovalent Interactions in the Design of Chiral Brønsted Acid Catalysts

Abstract

Chiral Bronsted acid catalysis is one of the most important tool in asymmetric synthesis. To achieve good reaction efficiency and selectivity, noncovalent interactions such as hydrogen bonding have been a key factor in the design of chiral Bronsted acid catalysts. Recent contributions in this area are summarized in this chapter.