Evaluation of Thyroid Function Tests among Chronic Kidney Disease Patients attended at a Tertiary Care Hospital in Dhaka City

Journal of National Institute of Neurosciences Bangladesh Pub Date : 2023-01-15 DOI:10.3329/jninb.v8i2.63750

Md Faruq Amin Talukder, Md Nazrul Islam, Eusha Ahmad Fidalillah Ansary, Md. Abdullah Al Mamun, Md Bellal Hossain, R. Naznin, Md. Nizam Uddin Chowdhury

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Abstract

Background: Serological status of thyroid hormones is important among chronic kidney disease patients. Objective: The purpose of the present study was to see the status of thyroid hormones among chronic kidney disease patients. Methodology: This cross-sectional study was done From January 2013 to December 2013 in the Department of Nephrology, Dhaka Medical College Hospital. A total of 50 diagnosed cases of adult male with different stages of CKD (CKD stage 3, 4, 5 and 5D) patients along with age-matched 51 healthy individuals were included. Serum Thyroid hormone T3 done by [1251] RIA kit, T4 done by T4 [1251] RIA kit, TSH level done by Turbo TSH [1251] IRMA kit. Result: A total number of 101 patients were recruited for this study of which 51 cases were in the group A and the rest of the 50 cases were in the group B. The mean serum T3 level was found 1.85±0.7 nmoL/L in group A and 2.79±0.55 nmoL/L in group B (p<0.05) which indicated that low serum T3 level was significantly associated with CKD. The mean serum T4 level was found 104.65±34.9 nmol/L in group A and 138.8±31.5 nmol/L in group B (p<0.05). Serum TSH level of the study patients showed that the mean serum TSH level was found 4.23±4.6 mIU/L in group A and 2.06±2.5mIU/L in group B (p<0.05). Conclusion: In conclusion the mean with SD of serum level of T3, T4 and TSH were significantly associated with chronic kidney disease. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):147-151

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达卡市三级医院慢性肾病患者甲状腺功能检查的评价

背景:甲状腺激素的血清学状态在慢性肾脏病患者中很重要。目的:了解慢性肾脏病患者甲状腺激素的状况。方法:本横断面研究于2013年1月至2013年12月在达卡医学院医院肾内科完成。本研究共纳入50例诊断为不同阶段CKD (CKD 3期、4期、5期和5D期)的成年男性患者以及51例年龄匹配的健康个体。血清甲状腺激素T3用[1251]RIA试剂盒检测，T4用T4 [1251] RIA试剂盒检测，TSH水平用Turbo TSH [1251] IRMA试剂盒检测。结果:本研究共纳入101例患者，其中A组51例，B组50例。A组平均血清T3水平为1.85±0.7 nmoL/L, B组平均血清T3水平为2.79±0.55 nmoL/L (p<0.05)，提示血清T3水平低与CKD有显著相关性。血清T4水平A组为104.65±34.9 nmol/L, B组为138.8±31.5 nmol/L (p<0.05)。研究患者血清TSH水平:A组平均TSH水平为4.23±4.6 mIU/L, B组平均TSH水平为2.06±2.5mIU/L (p<0.05)。结论:血清T3、T4、TSH水平与慢性肾脏疾病有显著相关性。孟加拉国国家神经科学研究所杂志，2022年7月;8(2):147-151

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Journal of National Institute of Neurosciences Bangladesh

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